Antimicrobial activity and cytotoxicity of bis(indole) alkaloids from the sponge Spongosorites sp.

@article{Oh2006AntimicrobialAA,
  title={Antimicrobial activity and cytotoxicity of bis(indole) alkaloids from the sponge Spongosorites sp.},
  author={Ki-bong Oh and Woongchon Mar and Sanghee Kim and Ji-Yun Kim and Tae-Hoon Lee and Jae-Gyu Kim and Daehyun Shin and Chung Ja Sim and Jongheon Shin},
  journal={Biological & pharmaceutical bulletin},
  year={2006},
  volume={29 3},
  pages={570-3}
}
Bis(indole) alkaloids, of the topsentin class (1-4) and hamacanthin class (5-9), isolated from the marine sponge Spongosorites sp. were investigated using several biological assays. In the evaluation of antimicrobial activity against various strains of bacteria and fungi, compounds of the hamacanthin class exhibited more potent antibacterial activity than… CONTINUE READING