Antimicrobial activities of 3-amino- and polyaminosterol analogues of squalamine and trodusquemine.

Abstract

A series of 3-amino- and polyaminosterol analogues of squalamine and trodusquemine were synthesized and evaluated for their in vitro antimicrobial properties against human pathogens. The activity was highly dependent on the structure of the different compounds involved and the best results were obtained with aminosterol derivatives 4b, 4e, 8b, 8e and 8n… (More)
DOI: 10.1080/14756360701809910

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