Antimicrobial Silk Clothing in the Treatment of Atopic Dermatitis Proves Comparable to Topical Corticosteroid Treatment

@article{Senti2006AntimicrobialSC,
  title={Antimicrobial Silk Clothing in the Treatment of Atopic Dermatitis Proves Comparable to Topical Corticosteroid Treatment},
  author={Gabriela Senti and Lisa S. Steinmann and Barbra Fischer and Roland Kurmann and Tazio Storni and P{\aa}l Johansen and Peter Schmid‐Grendelmeier and Brunello Wüthrich and Thomas M K{\"u}ndig},
  journal={Dermatology},
  year={2006},
  volume={213},
  pages={228 - 233}
}
Background: Atopic dermatitis (AD) is aggravated by mechanical irritation and bacterial colonization. Objective: This study compared the efficacy of an antimicrobial silk fabric (DermaSilk®) with that of a topical corticosteroid in the treatment of AD. Methods: Fifteen children were enrolled and wore a dress, where the left side was made of DermaSilk and the right side was made of cotton. The right arm and leg were treated daily with the corticosteroid mometasone for 7 days. The treatment… 

Evaluation of the Antibacterial Activity of a Special Silk Textile in the Treatment of Atopic Dermatitis

Although this special silk fabric seems to be able to improve skin lesions in AD, it was unable to demonstrate that such silk fabrics coated with AEGIS AEM 5572/5 have an antibacterial activity in vivo, as shown in vitro.

A proposal for the use of new silver-seaweed-cotton fibers in the treatment of atopic dermatitis

The results showed that the textile clothing with seaweed enriched with silver ions brings a quicker improvement of the patients in the first days in opposition to the use of standard all-cotton clothes, reinforcing the importance of non-pharmacological measures, like clothing, in the management of patients with a diagnosis of AD.

The Clinical Efficacy, Safety and Functionality of Anion Textile in the Treatment of Atopic Dermatitis

Anion textiles may be used to significantly improve the objective and subjective symptoms of AD, and are similar in terms of comfort to cotton textiles in patients suffering from AD.

DermaSilk in long-term control of infantile atopic dermatitis: a double blind randomized controlled trial.

This study shows that DermaSilk products can reduce relapses in infants with eczema during the maintenance phase and play a pivotal role in itching control, improving the quality of life of children and their family.

Functional textiles for atopic dermatitis: a systematic review and meta‐analysis

Recommendation for the use of functional textiles in AD treatment is weak, supported by low quality of evidence regarding effectiveness in AD symptoms and severity, with no evidence of hazardous consequences with their use.

A Randomized Double-Blind Study to Investigate the Clinical Efficacy of Adding a Non-Migrating Antimicrobial to a Special Silk Fabric in the Treatment of Atopic Dermatitis

This study demonstrates the importance of including the AEM 5772/5 finish to the specially knitted silk for a long-term improvement of atopic eczema symptoms.

A Real-Life Based Evaluation of the Effectiveness of Antibacterial Fabrics in Treating Atopic Dermatitis

  • D. Höfer
  • Medicine
    Dermatology research and practice
  • 2018
Considerable differences in the antibacterial effectiveness of conventional AD clothes were revealed, and garments were unable to modify skin colonization with S. aureus, although effectiveness can be triggered by wetting the garments.

The Effects of Fabric Containing Chamaecyparis obtusa Essential Oil on Atopic Dermatitis-Like Lesions: A Functional Clothing Possibility

Background: Essential oil derived from Chamaecyparis obtusa (EOCO) has been used as an alternative treatment for allergy-related diseases due to its immune-modulating characteristics. Clothing has

Epifibroin Powder 0039 for the Treatment of Seborrhoeic Dermatitis

  • Medicine
    International Journal of Clinical & Experimental Dermatology
  • 2020
Epifibroin Powder 0039 had about the same efficacy as methylprednisolone 1% cream and ketoconazole 2% cream in the treatment of SD without statistical significance, but could be of great benefit for the Treatment of SD.

Dermasilk Briefs in Vulvar Lichen Sclerosus: An Adjuvant Tool

Dermasilk fabric seems to be a useful adjunct to topical treatment in producing a better and more rapid control of symptoms in patients with LS.
...

References

SHOWING 1-10 OF 27 REFERENCES

Evaluation of the Antibacterial Activity of a Special Silk Textile in the Treatment of Atopic Dermatitis

Although this special silk fabric seems to be able to improve skin lesions in AD, it was unable to demonstrate that such silk fabrics coated with AEGIS AEM 5572/5 have an antibacterial activity in vivo, as shown in vitro.

Topical Steroids under Wet-Wrap Dressings in Atopic Dermatitis – A Vehicle-Controlled Trial

Application of the wet-wrap dressing technique for exacerbated AD lesions is effective, combination with a topical steroid being superior to a steroid-free application without bearing the risk of a bacterial superinfection.

Local steroid therapy and bacterial skin flora in atopic dermatitis

Results show the efficacy of topical corticosteroid treatment alone on S. aureus colonization in atopic skin, and confirm the critical role of inflammation in bacterial colonization.

Silver-Coated Textiles Reduce Staphylococcus aureus Colonization in Patients with Atopic Eczema

A superior improvement achieved by silver-coated compared to cotton textiles paralleled a potent anti-S.-aureus effect in atopic eczema.

Comparative effects of two topical antiseptics (chlorhexidine vs KMn04) on bacterial skin flora in atopic dermatitis.

The role and importance of the choice of a topical antiseptic in the treatment of AD is confirmed, with a clinical improvement noted in the two groups, though without statistical differences.

Beneficial Effects of Softened Fabrics on Atopic Skin

There is general concern about the possible cutaneous adverse effects of wearing garments treated with household laundry products, particularly on atopic skin. Our objective was to compare softened

Microbial colonization and atopic dermatitis

New insights into the important role of microorganisms and their key immunomodulatory pathways in atopic dermatitis may have important implications from a therapeutic point of view because patients with atopic Dermatitis may benefit from more than just anti-inflammatory treatment in the future.

[Textile intolerance in atopic eczema--a controlled clinical study].

The study clearly showed that the irritative capacity of synthetic shirts is significantly higher in patients with AD, while cotton shirts were best tolerated.

Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapy

A significant reduction of clinical severity was also observed after treatment with mupirocin, which was maintained over the following 4 weeks, although recolonization occurred during this period, with bacterial counts rising to pre‐treatment levels.

Microbial flora of atopic dermatitis.

The microbial flora of dermatitic skin, uninvolved skin, and the anterior nares of subjects with atopic eczema were investigated and Staphylococcus aureus was the predominant organism in the lesions and constituted 91% of the total aerobic bacterial flora.