Antimetastatic and antitumor activities of interleukin 10 in a murine model of breast cancer.

@article{Kundu1996AntimetastaticAA,
  title={Antimetastatic and antitumor activities of interleukin 10 in a murine model of breast cancer.},
  author={Namita Kundu and T L Beaty and Marion J. Jackson and Amy M. Fulton},
  journal={Journal of the National Cancer Institute},
  year={1996},
  volume={88 8},
  pages={536-41}
}
BACKGROUND Interleukin 10 (IL-10) is a potent immunoregulatory cytokine. It inhibits some cell functions, including T-helper (Th1) cell activity (i.e., interleukin 2 and interferon gamma production), and stimulates other functions such as a natural killer (NK) activity. In mice, IL-10 suppresses tumorigenicity in a xenograft system using a nonmetastasizing hamster cell line. PURPOSE We evaluated the antitumor and antimetastatic properties of IL-10 in syngeneic immunocompetent and… CONTINUE READING

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Interleukin 10 ( IL-10 ) is a potent immunoregulatory cytokine .
Interleukin 10 ( IL-10 ) is a potent immunoregulatory cytokine .
Interleukin 10 ( IL-10 ) is a potent immunoregulatory cytokine .
Interleukin 10 ( IL-10 ) is a potent immunoregulatory cytokine .
Interleukin 10 ( IL-10 ) is a potent immunoregulatory cytokine .
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