Antimetastatic Action and Hematological Toxicity of p-(3,3-Dimethyl-1- triazeno)benzoic Acid Potassium Salt and 5-(3,3-Dimethyl-1- triazeno)imidazole-4-carboxamide Used as Prophylactic Adjuvants to Surgical Tumor Removal in Mice Bearing B16 Melanoma1

Abstract

The treatment of mice bearing i.m. B16 melanoma with equitoxic dosages of the clinically used 5-(3,3-dimethyl-1-triazeno)¡midazole-4-carboxamide (DTIC) and of its benzenoid watersoluble analogue p-(3,3-dimethyl-1-triazeno)benzoic acid potas sium salt (DM-COOK) prior to surgical tumor removal results in a remarkable proportion of cures, even when the… (More)

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@inproceedings{Sava2006AntimetastaticAA, title={Antimetastatic Action and Hematological Toxicity of p-(3,3-Dimethyl-1- triazeno)benzoic Acid Potassium Salt and 5-(3,3-Dimethyl-1- triazeno)imidazole-4-carboxamide Used as Prophylactic Adjuvants to Surgical Tumor Removal in Mice Bearing B16 Melanoma1}, author={Gianni Sava and Tullio Giraldi and Lucia Lassiani and Carlo Nisi}, year={2006} }