Antimelanogenic effects of luteolin 7‐sulfate isolated from Phyllospadix iwatensis Makino

@article{Kwak2016AntimelanogenicEO,
  title={Antimelanogenic effects of luteolin 7‐sulfate isolated from Phyllospadix iwatensis Makino},
  author={Ju Young Kwak and Jin Kyung Seok and Hong Jin Suh and Y.-H. Choi and seo soo hong and D.-S. Kim and Yong Chool Boo},
  journal={British Journal of Dermatology},
  year={2016},
  volume={175}
}
Abnormal deposition of melanin may cause an aesthetic skin problem; therefore, the control of unwanted excessive melanin synthesis is the major goal of cosmetic research. 
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36 Citations
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Methods Citations
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36 Citations

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Citation Type

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Treatment with a mixture of S. japonicus extracts (MSCE) reduced melanin synthesis and tyrosinase activity in mouse melanocyte cells lines, B16F10 and Melan-A, indicating that MSCE may be useful as a potential skin-whitening compound in the skin medical industry.
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RTG can attenuate cellular melanin synthesis effectively through the suppression of MITF-dependent expression of melanogenic enzymes and the inhibition of catalytic activity of TYR enzyme, suggesting potential for use as a cosmeceutical ingredient for skin whitening.
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