Antimalarial efficacy of dynamic compound of plumbagin chemical constituent from Plumbago zeylanica Linn (Plumbaginaceae) against the malarial vector Anopheles stephensi Liston (Diptera: Culicidae)

@article{Pradeepa2014AntimalarialEO,
  title={Antimalarial efficacy of dynamic compound of plumbagin chemical constituent from Plumbago zeylanica Linn (Plumbaginaceae) against the malarial vector Anopheles stephensi Liston (Diptera: Culicidae)},
  author={Venkatraman Pradeepa and Subbiah Sathish-Narayanan and Suyambulingam Arunachalam Kirubakaran and Sengottayan Senthil-Nathan},
  journal={Parasitology Research},
  year={2014},
  volume={113},
  pages={3105-3109}
}
In the present investigation, the effective root compound of plumbagin of Plumbago zeylanica (Plumbaginaceae) was evaluated for chemical constituent and antimalarial effect against the fourth instar larvae of Anopheles stephensi Liston (Diptera). In the chromatographic analyses of root compound with Rf value of 0.788 and NMR analyses also revealed that the effective compound contain naphthoquinone plumbagin were identified as the major chemical constituent. Larval mortality was observed after 3… CONTINUE READING

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