Antilipidemic activity of 4-oxo-functionalized ethyl 6-chlorochroman-2-carboxylate analogs and a related tricyclic lactone in three rat models

Abstract

The synthesis of ethylcis-6-chloro-4-hydroxychroman-2-carboxylate (IV) and 6-chloro-4-hydroxychroman-2-carboxylic acid lactone (V) are reported. The antilipidemic properties of these compounds in 3 rat models were compared to the activity obtained for the previously synthesized related analogs ethyl 6-chlorochroman-2-carboxylate (II), ethyl 6… (More)
DOI: 10.1007/BF02534918

Topics

5 Figures and Tables

Cite this paper

@article{Cavestri1981AntilipidemicAO, title={Antilipidemic activity of 4-oxo-functionalized ethyl 6-chlorochroman-2-carboxylate analogs and a related tricyclic lactone in three rat models}, author={Richard Cavestri and J. A. Minatelli and Janice R. Baldwin and W. P. Loh and Dennis R. Feller and Howard A. I. Newman and C. L. Sober and Donald T. Witiak}, journal={Lipids}, year={1981}, volume={16}, pages={30-36} }