Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium.

@article{Tiuman2005AntileishmanialAO,
  title={Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium.},
  author={Tatiana Shioji Tiuman and T{\^a}nia Ueda-Nakamura and Di{\'o}genes Apar{\'i}cio Garcia Cortez and Benedito Prado Dias Filho and Jos{\'e} Andr{\'e}s Morgado-D{\'i}az and Wanderley de Souza and Celso Vataru Nakamura},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 1},
  pages={176-82}
}
The in vitro activity of parthenolide against Leishmania amazonensis was investigated. Parthenolide is a sesquiterpene lactone purified from the hydroalcoholic extract of aerial parts of Tanacetum parthenium. This isolated compound was identified through spectral analyses by UV, infrared, (1)H and (13)C nuclear magnetic resonance imaging, DEPT (distortionless enhancement by polarization transfer), COSY (correlated spectroscopy), HMQC (heteronuclear multiple-quantum coherence), and electron… CONTINUE READING