Antileishmanial Activity of Warifteine: A Bisbenzylisoquinoline Alkaloid Isolated from Cissampelos sympodialis Eichl. (Menispermaceae)

@article{Silva2012AntileishmanialAO,
  title={Antileishmanial Activity of Warifteine: A Bisbenzylisoquinoline Alkaloid Isolated from Cissampelos sympodialis Eichl. (Menispermaceae)},
  author={E. D. da Silva and Cynthia Dias Rayol and Paloma Lys Medeiros and R. Figueiredo and M{\'a}rcia Regina Piuvezan and Jos{\'e} Maria Brabosa-Filho and Alexsandro Fernandes Marinho and T. Silva and G. Milit{\~a}o and Ana Paula Pimentel Cassilhas and Paulo Paes de Andrade},
  journal={The Scientific World Journal},
  year={2012},
  volume={2012}
}
Leishmania (L.) chagasi is the etiological agent of visceral leishmaniasis, an important endemic zoonosis in the American continent, as well as in many other countries in Asia, Africa, and Mediterranean Europe. The treatment is difficult due to the high toxicity of the available drugs, high costs, and emergence of resistance in the parasites. Therefore, there is an urgent need for new leishmanicidal agents. The bisbenzylisoquinoline alkaloids have been related to antibacterial, antiprotozoal… Expand
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