Antiinflammatory C-glucosyl chromone from Aloe barbadensis.

@article{Hutter1996AntiinflammatoryCC,
  title={Antiinflammatory C-glucosyl chromone from Aloe barbadensis.},
  author={J A Hutter and Mustafa Salman and W. B. Stavinoha and Neera Satsangi and Robert F. Williams and Robert T. Streeper and Susan T. Weintraub},
  journal={Journal of natural products},
  year={1996},
  volume={59 5},
  pages={541-3}
}
A new antiinflammatory agent identified as 8-[C-beta-D-[2-O-(E)-cinnamoyl]glucopyranosyl]-2- [(R)-2-hydroxypropyl]-7-methoxy-5-methylchromone (1) has been isolated from Aloe barbadensis Miller. At a dose of 200 microg/mouse ear, 1 exhibited topical antiinflammatory activity equivalent to 200 microg/ear of hydrocortisone. There was no reduction in thymus weight caused by treatment with 1 for any of the doses tested, while 200 microg/ear of hydrocortisone resulted in a 50% decrease in thymus… CONTINUE READING

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At a dose of 200 microg / mouse ear , 1 exhibited topical antiinflammatory activity equivalent to 200 microg / ear of hydrocortisone .
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