Antihypertensive treatment in early postnatal life modulates prenatal dietary influences upon blood pressure in the rat.

@article{Sherman2000AntihypertensiveTI,
  title={Antihypertensive treatment in early postnatal life modulates prenatal dietary influences upon blood pressure in the rat.},
  author={Rachel C Sherman and Simon C. Langley-Evans},
  journal={Clinical science},
  year={2000},
  volume={98 3},
  pages={269-75}
}
Epidemiological evidence from diverse human populations, supported by experimental evidence from animal models, suggests that maternal nutrition during pregnancy is an important fetal programming influence upon cardiovascular disease. Experiments with a low-protein-diet model of rat pregnancy suggest a role for the renin-angiotensin system in the programming mechanism, since fetal undernutrition permanently elevates pulmonary and plasma angiotensin-converting enzyme activity. Long-term… CONTINUE READING
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The Biochemical Society and the Medical Research Society

  • S. C. Langley-Evans, G. J. Phillips, D. S. Gardner
  • 2000

Prenatal undernutrition alters postnatal vascular sensitivity to angiotensin II

  • D. S. Gardner, A. A. Jackson, S. C. Langley-Evans
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