Antihypertensive treatment and heart rate variability in diabetic patients: role of cardiac autonomic neuropathy.

@article{Salo1996AntihypertensiveTA,
  title={Antihypertensive treatment and heart rate variability in diabetic patients: role of cardiac autonomic neuropathy.},
  author={Tiina Marjatta Salo and Jorma S. A. Viikari and Kari J. Antila and Liisa-Maria Voipio-Pulkki and Jarmo O. Jalonen and Ilkka A. T. V{\"a}lim{\"a}ki},
  journal={Journal of the autonomic nervous system},
  year={1996},
  volume={60 1-2},
  pages={
          61-70
        }
}
Optimization of antihypertensive drug therapy continues to be a clinical challenge in patients with diabetes mellitus and its complications. We assessed the interference of autonomic neuropathy with drug effects on heart rate variability in 13 hypertensive diabetic subjects (mean age 48.4 years) during treatment with two blood pressure lowering drugs, metoprolol and enalapril. The baseline findings were compared with those obtained in 24 diabetic subjects without hypertension (mean age 32.5… CONTINUE READING
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