Antihypertensive therapy and quality of life: a comparison of atenolol, captopril, enalapril and propranolol.

@article{Steiner1990AntihypertensiveTA,
  title={Antihypertensive therapy and quality of life: a comparison of atenolol, captopril, enalapril and propranolol.},
  author={Solomon S. Steiner and Arnold J. Friedhoff and Bobby L. Wilson and Joachim Wecker and James P Di Santo},
  journal={Journal of human hypertension},
  year={1990},
  volume={4 3},
  pages={217-25}
}
This randomized, double-blind parallel study compared the effects of atenolol, captopril, enalapril and propranolol in 360 men with mild-to-moderate essential hypertension. Patients were titrated until diastolic blood pressure (Korotkoff phase V) decreased by at least 10 mmHg or to 90 mmHg or less. Quality of life assessments, based on validated psychometric questionnaires and objective measurements of cognitive function, occurred after three study phases: placebo run-in (3-5 weeks), titration… CONTINUE READING