Antihypertensive efficacy of FK906, a novel human renin inhibitor.

  title={Antihypertensive efficacy of FK906, a novel human renin inhibitor.},
  author={Toshio Ogihara and M. S. Nagano and Jitsuo Higaki and Koichi Higashimori and Kazuko Masuo and Hiroshi Mikami},
  journal={Clinical therapeutics},
  volume={15 3},
The antihypertensive efficacy of a newly developed orally active human renin inhibitor (FK906) was evaluated in 14 patients with essential hypertension aged 40 to 83 years (mean, 64 years). After a 1-week placebo run-in period, 25 mg of FK906 was given twice daily; this was increased up to 100 mg twice daily until sufficient blood pressure reduction was… CONTINUE READING