Antihypertensive effects of astaxanthin

@article{Yanai2008AntihypertensiveEO,
  title={Antihypertensive effects of astaxanthin},
  author={Hidekatsu Yanai and Kumie Ito and Hiroshi Yoshida and Norio Tada},
  journal={Integrated blood pressure control},
  year={2008},
  volume={1},
  pages={1 - 3}
}
Astaxanthin is a biological antioxidant naturally found in a wide variety of aquatic living organisms, and has shown various pharmacological activities, such as anti-inflammatory and antidiabetic activities. A recent study reported that the administration of astaxanthin induced a significant reduction in blood pressure and delayed the incidence of stroke in stroke-prone spontaneously hypertensive rats, suggesting that astaxanthin also has antihypertensive effect. In a study using aortic rings… Expand
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References

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TLDR
The results indicate that astaxanthin can exert beneficial effects in protection against hypertension and stroke and in improving memory in vascular dementia. Expand
Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo.
TLDR
This study suggests that AST has a dose-dependent ocular anti-inflammatory effect, by the suppression of NO, PGE2, and TNF-alpha production, through directly blocking NOS enzyme activity. Expand
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TLDR
The results suggest that ASX-O may act in modulating the blood fluidity in hypertension, and that the antihypertensive effects of ASX -O may be exerted through mechanisms including normalization of the sensitivity of the adrenoceptor sympathetic pathway, particularly [alpha]-adrenoceptors, and by restoration of the vascular tone through attenuation of the Ang II- and reactive oxygen species (ROS)-induced vasoconstriction. Expand
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TLDR
It is suggested that ASX-O can modulate the oxidative condition and may improve vascular elastin and arterial wall thickness in hypertension. Expand
Effect of astaxanthin on the hepatotoxicity, lipid peroxidation and antioxidative enzymes in the liver of CCl4-treated rats.
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TLDR
It is suggested that astaxanthin protects liver damage induced by CCl4 by inhibiting lipid peroxidation and stimulating the cellular antioxidant system. Expand
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The value of astaxanthin, a carotenoid pigment, in the treatment of oxidative injury is assessed. Astaxanthin protects the mitochondria of vitamin E-deficient rats from damage by Fe2(+)-catalyzedExpand
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TLDR
Results indicate that astaxanthin can exert beneficial effects in diabetes, with preservation of β-cell function, and suggests that anti-oxidants may be potentially useful for reducing glucose toxicity. Expand
Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice.
TLDR
Results indicate that astaxanthin can exert beneficial effects in diabetes, with preservation of beta-cell function, and suggests that anti-oxidants may be potentially useful for reducing glucose toxicity. Expand
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TLDR
Evidence is provided that consumption of marine animals producing astaxanthin inhibits LDL oxidation and possibly therefore contributes to the prevention of atherosclerosis. Expand
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TLDR
The current available evidence regarding astaxanthin chemistry and its potential beneficial effects in humans is reviewed and an unusual antioxidant activity which has caused a surge in the nutraceutical market for the encapsulated product is reviewed. Expand
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