Antihypertensive effects and mechanisms of chlorogenic acids

  title={Antihypertensive effects and mechanisms of chlorogenic acids},
  author={Youyou Zhao and Junkuan Wang and Olivier Ball{\`e}vre and Hongliang Luo and Weiguo Zhang},
  journal={Hypertension Research},
Chlorogenic acids (CGAs) are potent antioxidants found in certain foods and drinks, most notably in coffee. In recent years, basic and clinical investigations have implied that the consumption of chlorogenic acid can have an anti-hypertension effect. Mechanistically, the metabolites of CGAs attenuate oxidative stress (reactive oxygen species), which leads to the benefit of blood-pressure reduction through improved endothelial function and nitric oxide bioavailability in the arterial vasculature… CONTINUE READING