Antihypertensive drugs interacting with central imidazoline (I1)-receptors.

Abstract

Central imidazoline (I(1))-receptors have been recognised as targets of a new class of centrally acting antihypertensives. The stimulation of these I(1)-receptors induces peripheral sympatho-inhibition and a reduction of (elevated) blood pressure. Moxonidine and rilmenidine are the prototypes of this new class of centrally acting antihypertensives. These… (More)

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Cite this paper

@article{Zwieten1998AntihypertensiveDI, title={Antihypertensive drugs interacting with central imidazoline (I1)-receptors.}, author={Peter Adriaan van Zwieten}, journal={Expert opinion on investigational drugs}, year={1998}, volume={7 11}, pages={1781-93} }