Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials

@article{Gueyffier1999AntihypertensiveDI,
  title={Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials},
  author={F. Gueyffier and C. Bulpitt and J. Boissel and E. Schron and Indana Group},
  journal={The Lancet},
  year={1999},
  volume={353},
  pages={793-796}
}
BACKGROUND Beneficial clinical effects of treatment with antihypertensive drugs have been shown in middle-aged patients and in those hypertensive patients over 60 years old, but whether treatment is beneficial in patients over 80 years old is not known. METHODS We collected data from all participants aged 80 years and over in randomised controlled trials of antihypertensive drugs through direct contact with study investigators. Our primary outcome was fatal and non-fatal stroke. Secondary… Expand
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