Antihypertensive drugs and fibrinolytic function.

  title={Antihypertensive drugs and fibrinolytic function.},
  author={Roberto Fogari and Annalisa Zoppi},
  journal={American journal of hypertension},
  volume={19 12},
Impaired fibrinolytic function, characterized by increased plasminogen activator inhibitor type 1 (PAI-1) levels and decreased tissue plasminogen activator (t-PA) activity, has been found in patients with hypertension and may account in part for the increased risk of atherosclerosis and its clinical complications in these patients. Failure to correct this prothrombotic state may be one of the possible reasons for the disappointing effect of antihypertensive treatment on the incidence of… CONTINUE READING


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