Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats.

  title={Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats.},
  author={F L Hsu and I-Min Liu and D P Kuo and Wang-Chuan Chen and Hui-Chen Su and Juei Tang Cheng},
  journal={Journal of natural products},
  volume={66 6},
The antihyperglycemic action of puerarin, purified from the roots of Pueraria lobata, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Bolus intravenous injection of puerarin decreased the plasma glucose concentrations in a dose-dependent manner in STZ-diabetic rats. Similar treatment with puerarin also decreased the plasma glucose in normal rats, although the effect was not as great as that in STZ-diabetic rats. Puerarin at the effective dose (15.0 mg/kg… CONTINUE READING


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