Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors

@article{Taiwo2002AntihyperalgesicEO,
  title={Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors},
  author={Oludare B. Taiwo and Bradley K. Taylor},
  journal={Pain},
  year={2002},
  volume={96},
  pages={353-363}
}

Anti-nociceptive role of neuropeptide Y in the nucleus accumbens in rats with inflammation, an effect modulated by mu- and kappa-opioid receptors

Investigation of the effect of NPY in nociceptive modulation in the NAc of rats with inflammation, and the possible interation between NPY and the opioid systems suggests an involvement of antagonized the increased HWLs induced by preceding intra-NAc administration of the opioid antagonist nalozone.

Involvement of Neuropeptide Y in Post-Incisional Nociception in Rats

NPY is extensively expressed in the superficial laminae of the spinal cord and exhibit marked changes after incision, which indicates it is likely involved in post-incisional nociception.

Tonic inhibition of chronic pain by neuropeptide Y

Spinal NPY receptor systems are established as an endogenous braking mechanism that exerts a tonic, long-lasting, broad-spectrum inhibitory control of spinal nociceptive transmission, thus impeding the transition from acute to chronic pain.
...

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