Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2)in vitro

  title={Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2)in vitro},
  author={Su-Yun Lyu and Jee-Young Rhim and Won-Bong Park},
  journal={Archives of Pharmacal Research},
  • Su-Yun Lyu, Jee-Young Rhim, Won-Bong Park
  • Published 2005
  • Chemistry, Medicine
  • Archives of Pharmacal Research
  • Flavonoids, a group of low molecular weight phenylbenzopyrones, have various pharmacological properties including antioxidant, anticancer, bactericidal, and anti-inflammatory. We carried out anti-herpetic assays on 18 flavonoids in five classes and a virus-induced cytopathic effect (CPE) inhibitory assay, plaque reduction assay, and yield reduction assay were performed. When flavonoids were applied at various concentrations to Vero cells infected by HSV-1 and 2, most of the flavonoids showed… CONTINUE READING
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    Publications referenced by this paper.
    Antiviral effect of flavonoids on human viruses
    • 403
    Antiviral activity of natural occurring flavonoids in vitro.
    • 83
    Inhibition of virus multiplication and alteration of cyclic AMP level in cell cultures by flavonoids
    • 29
    Antiherpes virus activity of extracts from the medicinal plant Geranium sanguineum L.
    • 80
    Biological properties of citrus flavonoids pertaining to cancer and inflammation.
    • 461