Antigiardial Activity of Podophyllotoxin-Type Lignans from Bursera fagaroides var. fagaroides

  title={Antigiardial Activity of Podophyllotoxin-Type Lignans from Bursera fagaroides var. fagaroides},
  author={Filiberto Guti{\'e}rrez-Guti{\'e}rrez and Ana Mar{\'i}a Puebla-P{\'e}rez and Sirenia Gonz{\'a}lez-Pozos and J Manuel Hern{\'a}ndez-Hern{\'a}ndez and Armando P{\'e}rez-Rangel and Laura Alvarez and Gabriela Tapia-Pastrana and Araceli Castillo-Romero},
  journal={Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry},
Giardiasis, a diarrheal disease, is highly prevalent in developing countries. Several drugs are available for the treatment of this parasitosis; unfortunately, all of them have variable efficacies and adverse effects. Bursera fagaroides has been known for its anti-inflammatory and antidiarrheal properties in Mexican traditional medicine. We investigated the in vitro anti-giardial activities of four podophyllotoxin-type lignans from Bursera fagaroides var. fagaroides, namely, 5′-desmethoxy… 

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