Antigens in Immunity

@article{Nossal1964AntigensII,
  title={Antigens in Immunity},
  author={Gustav J. V. Nossal and A D Abbot and Judith Mitchell and Z. Lummus},
  journal={The Journal of Experimental Medicine},
  year={1964},
  volume={121},
  pages={945 - 954}
}
Flagellar antigens from S. adelaide bacteria were labelled with carrier-free (125)I so as to achieve a substitution rate of 0.1 to 2.1 radioactive iodine atoms per flagellin molecule. Lymph nodes from rats injected with small amounts of these antigens were teased into a single cell suspension. Single antibody-forming cells were identified and submitted individually to autoradiography so as to measure their content of iodine (125)I. The study was confined to the 7S phase of the primary response… CONTINUE READING