Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.

@article{Abraham2016AntigenotoxicEO,
  title={Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.},
  author={Suresh K. Abraham and Nidhi Khandelwal and Henning Hintzsche and Helga Stopper},
  journal={Mutagenesis},
  year={2016},
  volume={31 1},
  pages={
          27-33
        }
}
Experiments were performed to evaluate the in vitro and in vivo dose response for antigenotoxic effects of resveratrol (RES). For the in vitro study, HL-60 cells were co-treated with the test genotoxin and three concentrations of RES. Thereafter, genotoxic effects were assessed in the cytokinesis-block micronucleus test. Results of the in vitro experiments using genotoxins nitroquinoline-1-oxide (NQO) and mitomycin C (MMC) showed maximum inhibition of genotoxicity with the lowest test… Expand
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