Antigenicity of porcine cornea as xenograft.

PURPOSE To investigate the antigenicity of porcine corneal stroma as xenograft to man. METHODS The localization of alpha-gal epitope in the porcine eye was determined using biotinylated Griffonia simplicifolia 1 isolectin B4. Porcine corneal stromal was inserted into corneal stromal pockets of cynomolgus monkeys. Immunohistochemistry was performed to… CONTINUE READING