Antigenic variation among isolates of infectious salmon anaemia virus correlates with genetic variation of the viral haemagglutinin gene.

@article{Kibenge2001AntigenicVA,
  title={Antigenic variation among isolates of infectious salmon anaemia virus correlates with genetic variation of the viral haemagglutinin gene.},
  author={Frederick S B Kibenge and Molly J. T. Kibenge and P K McKenna and Paul Stothard and Rosalind Marshall and R Roland Cusack and Sandi McGeachy},
  journal={The Journal of general virology},
  year={2001},
  volume={82 Pt 12},
  pages={2869-79}
}
Infectious salmon anaemia virus (ISAV), an orthomyxovirus-like virus, is an important fish pathogen in marine aquaculture. Virus neutralization of 24 ISAV isolates in the TO cell line using rabbit antisera to the whole virus and comparative sequence analysis of their haemagglutinin (HA) genes have allowed elaboration on the variation of ISAV isolates. The 24 viruses were neutralized to varying degrees, revealing two major antigenic groups, one American and one European. Sequence analysis of the… CONTINUE READING
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Family Orthomyxoviridae

  • N. J. Cox, F. Fuller, +8 authors R. Webster
  • In Virus Taxonomy. Seventh Report of the…
  • 2000
Highly Influential
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