Antigenic heterogeneity of rat macrophages. A monoclonal antibody reacting only with alveolar but not with other types of macrophages.

Abstract

Hybridoma antibodies were produced by fusing spleen cells from mice immunized with rat alveolar macrophages (AM) with P3 x 63Ag8/653 myeloma cells. Some of the hybridomas were processed to achieve monoclonality. Reactivity was tested in an indirect membrane immunofluorescence assay. One of the monoclonal antibodies, called VEP6 antibody, reacted with rat AM… (More)

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