Antigenic differences between primary methylcholanthrene-induced rat sarcomas and post-surgical recurrences.

@article{Pimm1977AntigenicDB,
  title={Antigenic differences between primary methylcholanthrene-induced rat sarcomas and post-surgical recurrences.},
  author={Malcolm V. Pimm and Robert W. Baldwin},
  journal={International journal of cancer},
  year={1977},
  volume={20 1},
  pages={37-43}
}
The immunogenicities of in vivo lines established from primary MCA-induced rat sarcomas have been compared with those of lines initiated from tumour recurrences at the site of the primaries' surgical excisions. Lines from two of four primary sarcomas showed little or no immunogenicity, as assessed by protection against challenge afforded by graft excision or implantation of irradiated tissue. In contrast, lines from all four recurrences were immunogenic, giving protection against up to 5 X 10(6… CONTINUE READING

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