Antigenic complementarity between HIV and other AIDS-associated infections results in idiotype-antiidiotype antibody complexes that cross react with lymphocyte proteins.

Abstract

HIV proteins mimic HLA proteins, and the proteins of cofactor infections (cytomegalovirus, hepatitis viruses, mycobacteria, mycoplasmas) mimic CD4 proteins, making some HIV antigens molecularly complementary to cofactor antigens. Antibodies to HIV and its cofactors should therefore act like idiotype-antiidiotype pairs. Over 2000 combinations of antibodies… (More)

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@article{RootBernstein2005AntigenicCB, title={Antigenic complementarity between HIV and other AIDS-associated infections results in idiotype-antiidiotype antibody complexes that cross react with lymphocyte proteins.}, author={Robert Root-Bernstein}, journal={Vaccine}, year={2005}, volume={23 17-18}, pages={2160-3} }