Antigen-specific induction of regulatory T cells for type 1 diabetes therapy.

@article{Filippi2005AntigenspecificIO,
  title={Antigen-specific induction of regulatory T cells for type 1 diabetes therapy.},
  author={Christophe M. Filippi and Damien Bresson and Matthias G von Herrath},
  journal={International reviews of immunology},
  year={2005},
  volume={24 5-6},
  pages={341-60}
}
Since their discovery decades ago, regulatory T (Treg) cells have prompted many investigations into their potential role in the generation or prevention of autoimmune disorders such as type 1 diabetes (T1D). Initially identified based on their ability to maintain tolerance to self-antigens in peripheral organs, Treg cells have since been efficiently induced therapeutically and shown to prevent the progression of T1D as well as other autoimmune diseases. Beneficial modification of immunity… CONTINUE READING