Corpus ID: 2293495

Antigen-specific human T lymphocyte clones: viral antigen specificity of influenza virus-immune clones.

  title={Antigen-specific human T lymphocyte clones: viral antigen specificity of influenza virus-immune clones.},
  author={J. Lamb and D. Eckels and M. Phelan and P. Lake and J. Woody},
  journal={Journal of immunology},
  volume={128 3},
Human T lymphocyte clones (TLC) specific for type A (A/Texas/1/77) influenza virus and maintained in continuous culture with T cell growth factor, were analyzed to define the cellular specificity pattern of virus recognition. A panel of TLC were stimulated with strains of serologically characterized type A influenza subtypes. Five TLC recognized all the viral subtypes; the remaining clones recognized only subtypes that shared serologically defined determinants with the immunizing subtype. In… Expand
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