Antigen-specific T cells maintain an effector memory phenotype during persistent Trypanosoma cruzi infection.

@article{Martin2005AntigenspecificTC,
  title={Antigen-specific T cells maintain an effector memory phenotype during persistent Trypanosoma cruzi infection.},
  author={Diana L Martin and Rick L. Tarleton},
  journal={Journal of immunology},
  year={2005},
  volume={174 3},
  pages={
          1594-601
        }
}
  • Diana L Martin, Rick L. Tarleton
  • Published in Journal of immunology 2005
  • Biology, Medicine
  • Infection with the protozoan parasite Trypanosoma cruzi is a major cause of morbidity and mortality in Central and South America. Control of acute experimental infection with T. cruzi is dependent on a robust T cell and type 1 cytokine response. However, little evidence exists demonstrating the development and persistence of a potent antiparasite T cell memory response, and there has been much speculation that the majority of the immune response to T. cruzi infection is not directed against the… CONTINUE READING

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