Antigen-specific, I-a-restricted Suppressor Hybridomas with Spontaneous Cytolytic Activity Functional Properties and Lack of Rearrangement of the T Cell Receptor/3 Chain Genes


Since their discovery in 1971 (1, 2), T suppressor (Ts) ~ cells have been the object o f numerous studies. Particularly helpful in the characterizat ion of Ts cells was the establishment of cloned T cell lines, such as T cell hybridomas, long-term T cell lines, or t rans formed T cells (for a survey see 3). A surprisingly large number o f Ts subpopulat ions… (More)


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