Antigen sampling in the small intestine.

  title={Antigen sampling in the small intestine.},
  author={Olga Schulz and Oliver Pabst},
  journal={Trends in immunology},
  volume={34 4},
Active sampling of intestinal antigen initiates regulated immune responses that ensure intestinal homeostasis. Several specialized mechanisms transport luminal antigen across the gut epithelium. Epithelium overlying lymphoid compartments is equipped with transcytotic microfold (M) cells that transport particulate material either directly or with the help of dendritic cells (DCs). By contrast, normal villous epithelium transports antigen by means of antigen-shuttling receptors together with… CONTINUE READING