Antigen sampling across epithelial barriers and induction of mucosal immune responses.

@article{Neutra1996AntigenSA,
  title={Antigen sampling across epithelial barriers and induction of mucosal immune responses.},
  author={Marian R. Neutra and Eric Pringault and J. P. Kraehenbuhl},
  journal={Annual review of immunology},
  year={1996},
  volume={14},
  pages={275-300}
}
Epithelial barriers on mucosal surfaces at different sites in the body differ dramatically in their cellular organization, and antigen sampling strategies at diverse mucosal sites are adapted accordingly. In stratified and pseudostratified epithelia, dendritic cells migrate to the outer limit of the epithelium, where they sample antigens for subsequent presentation in local or distant organized lymphoid tissues. In simple epithelia, specialized epithelial M cells (a phenotype that occurs only… CONTINUE READING

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