Antigen presentation events in autoimmune diabetes.

@article{Calderon2012AntigenPE,
  title={Antigen presentation events in autoimmune diabetes.},
  author={Boris Calderon and Emil R Unanue},
  journal={Current opinion in immunology},
  year={2012},
  volume={24 1},
  pages={119-28}
}
Antigen presenting cells (APC) be they dendritic cells (DC) or macrophages reside in all tissues. Their role varies from presenting antigen, clearing the tissue from unwanted material, helping in the remodeling that follows injury and inflammation, to a supporting or trophic function. Their features, biology, and turnover may be unique for each organ, modulated by the particular anatomy and physiology of the tissue. These features affect the handling and presentation of antigens, either… CONTINUE READING

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