Antigen presentation by a continuous human microvascular endothelial cell line, HMEC-1, to human T cells.

Abstract

Endothelial cells line the vessels and lymphatics of the body, acting as a barrier between the blood and extravascular tissue. These cells are, therefore, in a prime position to play a role in lymphocyte activation. Indeed, it has been shown that primary endothelial cells in culture are capable of presenting particulate and soluble antigens to T cells and… (More)

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