Antigen presentation by CD1 and MHC-encoded class I-like molecules.

@article{Melin1996AntigenPB,
  title={Antigen presentation by CD1 and MHC-encoded class I-like molecules.},
  author={August{\'i}n Meli{\'a}n and Evan M. Beckman and Steven A. Porcelli and Michael B Brenner},
  journal={Current opinion in immunology},
  year={1996},
  volume={8 1},
  pages={
          82-8
        }
}
Three known lineages of antigen-presenting molecules restrict T-cell responses to microbial antigens: MHC class I and MHC encoded class I like molecules present peptides derived from the proteolysis of intracellular pathogens, MHC class ii molecules present peptides derived from the proteolysis of extracellular pathogens and CD1 molecules present unique microbial lipids and glycolipids. Recent studies have indicated that CD1 molecules mediate a novel system of antigen presentation and that MHC… CONTINUE READING

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