Antigen-induced secretion of histamine and the phosphorylation of myosin by protein kinase C in rat basophilic leukemia cells.

Abstract

IgE-mediated stimulation of rat basophilic leukemia (RBL-2H3) cells results in the secretion of histamine. Myosin immunoprecipitated from these cells shows an increase in the amount of radioactive phosphate incorporated into its heavy (200 kDa) and light (20 kDa) chains. In unstimulated cells two-dimensional mapping of tryptic peptides of the myosin light… (More)

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@article{Ludowyke1989AntigeninducedSO, title={Antigen-induced secretion of histamine and the phosphorylation of myosin by protein kinase C in rat basophilic leukemia cells.}, author={Russell I Ludowyke and Ika I Peleg and Michael A. Beaven and Raquel Adelstein}, journal={The Journal of biological chemistry}, year={1989}, volume={264 21}, pages={12492-501} }