Antigen-induced IL-10+ regulatory T cells are independent of CD25+ regulatory cells for their growth, differentiation, and function.

@article{Nicolson2006AntigeninducedIR,
  title={Antigen-induced IL-10+ regulatory T cells are independent of CD25+ regulatory cells for their growth, differentiation, and function.},
  author={Kirsty S. Nicolson and Emma J O'neill and Anette Sundstedt and Heather B. Streeter and Sophie Minaee and David Cameron Wraith},
  journal={Journal of immunology},
  year={2006},
  volume={176 9},
  pages={
          5329-37
        }
}
Recent studies have emphasized the importance of T cells with regulatory/suppressor properties in controlling autoimmune diseases. A number of different types of regulatory T cells have been described with the best characterized being the CD25(+) population. In addition, it has been shown that regulatory T cells can be induced by specific Ag administration. In this study, we investigate the relationship between peptide-induced, CD4(+) regulatory T cells and naturally occurring CD4(+)CD25… CONTINUE READING
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