Antigen handling in the intestine mediated by normal enterocytes

@inproceedings{Mayer1990AntigenHI,
  title={Antigen handling in the intestine mediated by normal enterocytes},
  author={Lloyd R Mayer and Edward J. Siden and Susanne Becker and Dieter Eisenhardt},
  year={1990}
}
The co-existence of a myriad of foreign antigens in the intestinal lumen alongside immunocompetent cells has resulted in the evolution of a specialized mucosal immune system. A natural physical barrier to antigen has been the intestinal enterocyte joined to its neighbors by desmosomes forming tight junctions. Therefore, specialized antigen sampling cells, follicle associated epithelium or M cells, were thought to be the major sites for antigen entry into the mucosa associated lymphoid tissue… CONTINUE READING

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