Antigen-driven focal inflammatory death of malaria liver stages

@inproceedings{Bayarsaikhan2015AntigendrivenFI,
  title={Antigen-driven focal inflammatory death of malaria liver stages},
  author={Ganchimeg Bayarsaikhan and Masoud Akbari and Katsuyuki Yui and Rogerio Amino},
  booktitle={Front. Microbiol.},
  year={2015}
}
Multiple immunizations using live irradiated sporozoites, the infectious plasmodial stage delivered into the host skin during a mosquito bite, can elicit sterile immunity to malaria. CD8(+) T cells seem to play an essential role in this protective immunity, since their depletion consistently abolishes sterilizing protection in several experimental models. So far, only a few parasite antigens are known to induce CD8(+) T cell-dependent protection, but none of them can reach the levels of… CONTINUE READING
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References

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Showing 1-10 of 62 references

The complexity of protective immunity

  • S. L. Hoffman
  • 2000
Highly Influential
6 Excerpts

CD8 T-cell-mediated protection against liver-stage malaria: lessons from a mouse model

  • N. Van Braeckel-Budimir, J. T. Harty
  • Front. Microbiol
  • 2014
1 Excerpt

A T-cell response

  • S. C. Murphy, A. Kas, B. C. Stone, M. J. Bevan
  • Nature
  • 2013
2 Excerpts

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