Antigen distribution in a latex suspension and its relationship to test sensitivity.

@article{Hechemy1976AntigenDI,
  title={Antigen distribution in a latex suspension and its relationship to test sensitivity.},
  author={Karim E. Hechemy and R William C Stevens and Hazem A Gaafar},
  journal={Journal of clinical microbiology},
  year={1976},
  volume={4 1},
  pages={82-6}
}
Specific aggregation of latex particles due to antigen-antibody reaction occurred only when antigen was latex bound, as found in a study using Escherichia coli 0111:B4 extract. Maximum serological sensitivity was achieved when free antigen was present in a narrow range of ratios with the bound antigen.