Antigen detection in the diagnosis of invasive aspergillosis. Utility in controlled, blinded trials.

@article{Weiner1983AntigenDI,
  title={Antigen detection in the diagnosis of invasive aspergillosis. Utility in controlled, blinded trials.},
  author={Marc H Weiner and George Harrison Talbot and Stanton L. Gerson and Gaetano Filice and Peter A. Cassileth},
  journal={Annals of internal medicine},
  year={1983},
  volume={99 6},
  pages={
          777-82
        }
}
Two blinded, controlled trials were done to evaluate the usefulness of fungal antigen detection for the diagnosis of invasive aspergillosis. Detection of Aspergillus fumigatus carbohydrate by radioimmunoassay was compared with antibody detection by an enzyme-linked immunosorbent assay and with diagnostic microbiologic and histopathologic procedures. In the first trial, antigenemia was detected in 4 of 6 leukemic patients with invasive pulmonary aspergillosis, but not in 8 acute leukemic… CONTINUE READING
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