Antigen-dependent increase in cytosolic free calcium in specific human T-lymphocyte clones

Abstract

Calcium has been implicated as an intracellular messenger in the cellular response to various external stimuli. Exposure of lymphocytes to various mitogens and lectins results in rapid transmembrane calcium fluxes1–3 and increased cytoplasmic calcium concentrations ([Ca2+]i)4–7. It is not clear, however, whether the mechanisms by which these non… (More)
DOI: 10.1038/316545a0

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