Antigen- and isotype-specific regulation of IgE responses by Lyt 1+,2,3- and Lyt 1-,2,3+ T suppressor cells.


Antigen-specific, IgE isotype-selective suppression is induced following treatment of mice with a high-molecular-weight glutaraldehyde-polymerized ovalbumin preparation (OA-POL). The results show that the suppression is mediated by Lyt 1+,2,3- cells residing in the spleen. Adoptive transfer experiments indicate that Lyt 2,3+ or Lyt 1,2,3+ cells are not… (More)


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