Antifungal triterpene glycosides from the sea cucumber Holothuria (Microthele) axiloga.

  title={Antifungal triterpene glycosides from the sea cucumber Holothuria (Microthele) axiloga.},
  author={Wei-Hua Yuan and Yang-hua Yi and Ren-Xiang Tan and Zeng-lei Wang and Guoquan Sun and Mei Xue and Hongwei Zhang and Hai-Feng Tang},
  journal={Planta medica},
  volume={75 6},
Three new holostan-type triterpene glycosides, arguside F (1), impatienside B (2), and pervicoside D (3), together with a known saponin, holothurin B ( 4) were isolated from the sea cucumber Holothuria (Microthele) axiloga H. L. Clark. On the basis of spectroscopic data and chemical reactions, the structures of the new compounds were elucidated. Compound 2 showed significant antifungal activities against six strains (1 < or = MIC(80) < or = 4 microg/mL). The stereochemistry of holothurin B (4… 

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