Antifungal susceptibilities of clinical and environmental isolates of Cryptococcus neoformans in Goiânia city, Goiás, Brazil.

  title={Antifungal susceptibilities of clinical and environmental isolates of Cryptococcus neoformans in Goi{\^a}nia city, Goi{\'a}s, Brazil.},
  author={L{\'u}cia Kioko Hasimoto e Souza and Orionalda de F{\'a}tima Lisboa Fernandes and Cl{\'a}udia Castelo Branco Artiaga Kobayashi and Xisto Sena Passos and Carolina Rodrigues Costa and Janine de Aquino Lemos and Ary Henrique Souza-J{\'u}nior and Maria do Ros{\'a}rio Silva},
  journal={Revista do Instituto de Medicina Tropical de Sao Paulo},
  volume={47 5},
We evaluated the antifungal activities of amphotericin B, fluconazole, itraconazole and voriconazole in 70 Cryptococcus neoformans strains obtained from cerebrospinal fluid from AIDS patients and 40 C. neoformans strains isolated from the environment. Four clinical isolates were identified as C. neoformans var. gattii. The susceptibility test was done using a broth microdilution method according to NCCLS M27-A2. Range minimal inhibitory concentrations (MICs) for C. neoformans clinical isolates… CONTINUE READING


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